Can-Change members C.R. Rouleau and T.S. Campbell were involved in a study exploring patients’ decision-making about enrolling into a cardiac rehabilitation program. Anticipated benefit, perceived ability, and contextual influences were themes that emerged from the face-to-face interviews with patients. Individualized efforts to resolve ambivalence, address knowledge gaps, and problem-solve barriers may increase patients’ uptake of cardiac rehabilitation programs as effective secondary prevention strategy.